Recent research from the University of Auckland has found that the drug alpelisib is capable of increasing lifespan. In a study conducted on mice, it was found that the drug extended the lifespan of the mice by an average of 10%, with some mice living up to three years longer. The mice also showed signs of improved health in old age, such as improved coordination and strength. However, there were also some negative aging markers, such as lower bone mass.
Dr. Chris Hedges, a research fellow on the team, commented that “Aging is not only about lifespan but also about quality of life.” The team noted that much more research needs to be done before the drug can be safely recommended to humans. The drug works by targeting the PI 3-kinase enzyme and the findings of the study have shown that these drugs may have uses in other areas, and revealed novel mechanisms contributing to age-related diseases.
This research provides valuable insight into the potential of using drugs to target PI 3-kinase to increase lifespan and improve quality of life. While the results of this study are promising, more research needs to be conducted before the drug can be safely recommended to humans. It is important to note that the study was conducted on mice, and the results may not be the same in humans.