A new male contraceptive drug has been developed that could revolutionize birth control. In a study conducted on mice, the drug was 100% effective in preventing pregnancy for around two hours, with no adverse side effects.
The drug works by inhibiting the production of a protein called soluble adenylyl cyclase (sAC) which is necessary for sperm to be able to move. With the protein inhibited, sperm are temporarily immobile and unable to travel up the vaginal tract to fertilize an egg.
In the study, male mice were given the drug and then paired with female mice after 30 minutes. After 2 hours of mating, there were no resulting pregnancies, indicating the drug was 100% effective. The drug also did not cause any side effects when given three times the standard dose for 42 days.
If the drug proves to be equally as effective in humans, it could offer men the first 'on-demand' male birth control pill. It would act rapidly and temporarily, potentially changing the way men and women view birth control. The researchers plan to refine the drug and hope to begin clinical trials by 2025.